ES8601987A1 - Un procedimiento para preparar derivados de acido 4,7-dihidropirazolo (3,4-b)piridin-5-carboxilico - Google Patents
Un procedimiento para preparar derivados de acido 4,7-dihidropirazolo (3,4-b)piridin-5-carboxilicoInfo
- Publication number
- ES8601987A1 ES8601987A1 ES528152A ES528152A ES8601987A1 ES 8601987 A1 ES8601987 A1 ES 8601987A1 ES 528152 A ES528152 A ES 528152A ES 528152 A ES528152 A ES 528152A ES 8601987 A1 ES8601987 A1 ES 8601987A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- opt
- phenyl
- substd
- pyrazolopyridines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000005229 pyrazolopyridines Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 11
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
- 125000003342 alkenyl group Chemical group 0.000 abstract 3
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000000538 pentafluorophenyl group Chemical group FC1=C(F)C(F)=C(*)C(F)=C1F 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8236131 | 1982-12-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES528152A0 ES528152A0 (es) | 1985-11-16 |
| ES8601987A1 true ES8601987A1 (es) | 1985-11-16 |
Family
ID=10535093
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES528152A Expired ES8601987A1 (es) | 1982-12-20 | 1983-12-19 | Un procedimiento para preparar derivados de acido 4,7-dihidropirazolo (3,4-b)piridin-5-carboxilico |
| ES532124A Granted ES532124A0 (es) | 1982-12-20 | 1984-05-03 | Un procedimiento para preparar derivados de acido 4, 7-dihidropirazolo (3, 4-b) piridin-5-carboxilico |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES532124A Granted ES532124A0 (es) | 1982-12-20 | 1984-05-03 | Un procedimiento para preparar derivados de acido 4, 7-dihidropirazolo (3, 4-b) piridin-5-carboxilico |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4954508A (en]) |
| EP (1) | EP0114273B1 (en]) |
| JP (1) | JPH0660181B2 (en]) |
| KR (1) | KR890002227B1 (en]) |
| AT (1) | ATE69227T1 (en]) |
| AU (1) | AU574654B2 (en]) |
| DE (1) | DE3382452D1 (en]) |
| DK (1) | DK582083A (en]) |
| ES (2) | ES8601987A1 (en]) |
| FI (1) | FI76337C (en]) |
| GR (1) | GR79111B (en]) |
| IE (1) | IE57305B1 (en]) |
| IL (1) | IL70445A (en]) |
| MY (1) | MY101250A (en]) |
| NO (1) | NO160367C (en]) |
| NZ (1) | NZ206626A (en]) |
| PH (1) | PH20896A (en]) |
| PT (1) | PT77850B (en]) |
| ZA (1) | ZA839092B (en]) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5965089A (ja) * | 1982-10-05 | 1984-04-13 | Shionogi & Co Ltd | ジヒドロピラゾロ〔３，４−ｂ〕ピリジン誘導体およびその製造法 |
| US4873334A (en) * | 1982-10-05 | 1989-10-10 | Shionogi & Co., Ltd. | 4,7-dihydropyrazolo(3,4-b) pyridine derivatives |
| JPS60197685A (ja) * | 1984-03-19 | 1985-10-07 | Shionogi & Co Ltd | ４，７―ジヒドロピラゾロ［３，４―ｂ］ピリジン誘導体とその製造法 |
| JPS6056979A (ja) * | 1983-09-08 | 1985-04-02 | Shionogi & Co Ltd | ４，７−ジヒドロピラゾロ〔３，４−ｂ〕ピリジン誘導体およびその製造法 |
| US4918074A (en) * | 1984-03-12 | 1990-04-17 | Yoshitomi Pharmaceutical Industries, Ltd. | Polyazaheterocycle compounds |
| US4916140A (en) * | 1988-09-28 | 1990-04-10 | Merrell Dow Pharmaceuticals Inc. | Antiepileptic pyrazolopyridines |
| JP2005501800A (ja) * | 2001-02-02 | 2005-01-20 | 三菱ウェルファーマ株式会社 | ジヒドロピラゾロピリジン化合物およびその医薬用途 |
| US6977262B2 (en) | 2001-02-02 | 2005-12-20 | Mitsubishi Pharma Corporation | Dihydropyrazolopyridine compounds and pharmaceutical use thereof |
| WO2005016245A2 (en) * | 2003-06-13 | 2005-02-24 | Zentaris Gmbh | Compounds having inhibitive activity of phosphatidylinositol 3-kinase and methods of use thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773778A (en) * | 1972-01-24 | 1973-11-20 | Squibb & Sons Inc | Sulfur derivatives of pyrazolo (3,4-b)pyridines |
| DE2356684A1 (de) * | 1972-11-15 | 1974-05-16 | Heyden Chem Fab | Neue 4-aminoderivate von pyrazolo (3,4-b)pyridin-5-carboxamiden |
| US4038283A (en) * | 1975-04-30 | 1977-07-26 | E. R. Squibb & Sons, Inc. | 4-Alkoxy or hydroxy derivatives of 2H-pyrazolo[3,4-b]pyridine-5-carboxylic acids and esters |
| GB1568399A (en) * | 1975-10-16 | 1980-05-29 | Squibb & Sons Inc | Pyrazolo pyridine derivatives |
| US4020072A (en) * | 1976-05-04 | 1977-04-26 | E. R. Squibb & Sons, Inc. | 5-Aminomethyl-1H-pyrazolo[3,4-b]pyridines |
| NZ201395A (en) * | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
| JPS5965089A (ja) * | 1982-10-05 | 1984-04-13 | Shionogi & Co Ltd | ジヒドロピラゾロ〔３，４−ｂ〕ピリジン誘導体およびその製造法 |
-
1983
- 1983-12-02 GR GR73149A patent/GR79111B/el unknown
- 1983-12-06 AT AT83112273T patent/ATE69227T1/de not_active IP Right Cessation
- 1983-12-06 EP EP83112273A patent/EP0114273B1/en not_active Expired - Lifetime
- 1983-12-06 DE DE8383112273T patent/DE3382452D1/de not_active Expired - Fee Related
- 1983-12-07 ZA ZA839092A patent/ZA839092B/xx unknown
- 1983-12-09 AU AU22270/83A patent/AU574654B2/en not_active Ceased
- 1983-12-14 IL IL70445A patent/IL70445A/xx unknown
- 1983-12-16 DK DK582083A patent/DK582083A/da not_active Application Discontinuation
- 1983-12-19 JP JP58238063A patent/JPH0660181B2/ja not_active Expired - Lifetime
- 1983-12-19 IE IE2988/83A patent/IE57305B1/en not_active IP Right Cessation
- 1983-12-19 NZ NZ206626A patent/NZ206626A/en unknown
- 1983-12-19 NO NO834695A patent/NO160367C/no unknown
- 1983-12-19 KR KR1019830005999A patent/KR890002227B1/ko not_active Expired
- 1983-12-19 ES ES528152A patent/ES8601987A1/es not_active Expired
- 1983-12-19 PT PT77850A patent/PT77850B/pt not_active IP Right Cessation
- 1983-12-19 FI FI834661A patent/FI76337C/fi not_active IP Right Cessation
- 1983-12-20 PH PH30003A patent/PH20896A/en unknown
-
1984
- 1984-05-03 ES ES532124A patent/ES532124A0/es active Granted
-
1987
- 1987-06-18 MY MYPI87000836A patent/MY101250A/en unknown
-
1988
- 1988-12-20 US US07/286,917 patent/US4954508A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2227083A (en) | 1984-06-28 |
| IE832988L (en) | 1984-06-20 |
| KR840007000A (ko) | 1984-12-04 |
| DK582083A (da) | 1984-06-21 |
| JPS59118786A (ja) | 1984-07-09 |
| IL70445A (en) | 1988-12-30 |
| NZ206626A (en) | 1986-11-12 |
| NO160367B (no) | 1989-01-02 |
| ES8506016A1 (es) | 1985-06-16 |
| EP0114273A1 (en) | 1984-08-01 |
| AU574654B2 (en) | 1988-07-14 |
| FI76337B (fi) | 1988-06-30 |
| NO834695L (no) | 1984-06-21 |
| ATE69227T1 (de) | 1991-11-15 |
| PT77850B (en) | 1986-05-08 |
| EP0114273B1 (en) | 1991-11-06 |
| KR890002227B1 (ko) | 1989-06-24 |
| PH20896A (en) | 1987-05-27 |
| FI76337C (fi) | 1988-10-10 |
| IL70445A0 (en) | 1984-03-30 |
| ES528152A0 (es) | 1985-11-16 |
| GR79111B (en]) | 1984-10-02 |
| FI834661A7 (fi) | 1984-06-21 |
| NO160367C (no) | 1989-04-12 |
| US4954508A (en) | 1990-09-04 |
| DE3382452D1 (de) | 1991-12-12 |
| PT77850A (en) | 1984-01-01 |
| ES532124A0 (es) | 1985-06-16 |
| IE57305B1 (en) | 1992-07-15 |
| JPH0660181B2 (ja) | 1994-08-10 |
| DK582083D0 (da) | 1983-12-16 |
| FI834661A0 (fi) | 1983-12-19 |
| MY101250A (en) | 1991-08-17 |
| ZA839092B (en) | 1984-07-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970303 |